This is Dr. Josh Stender’s papers on ER signalling and how cytokines can help breast cancer cells achieve the ability to become more aggressive and resistant to endocrine deprivation based therapies. As a young investigator, I learned a tremendous amount about science from Josh, his labmates and his supervisor. I’m glad that he asked us to do some extravasation assays and I’m glad that it all was consistent with his in vitro findings. Cheers!